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Routine maintenance of an suitable airway, with assisted respiration and oxygen administration as important.

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Phenobarbital seems to interfere Along with the absorption of orally administered griseofulvin, As a result decreasing its blood stage.

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Phenobarbital has become shown to shorten the half-lifetime of doxycycline for as long as 2 weeks following barbiturate therapy is discontinued. This mechanism might be through the induction of hepatic microsomal enzymes that metabolize the antibiotic.

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